null

SMILES: CC(=O)NC1(CCCC1)C(=O)NCc1cccc(c1)-n1nc(cc1NC(=O)Nc1ccccc1)C(C)(C)C

InChI Key: InChIKey=DDEZUQPFAQQFFP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50323422 (1-acetamido-N-(3-(3-tert-butyl-5-(3-phenylureido)-...) Show SMILES CC(=O)NC1(CCCC1)C(=O)NCc1cccc(c1)-n1nc(cc1NC(=O)Nc1ccccc1)C(C)(C)C Show InChI InChI=1S/C29H36N6O3/c1-20(36)33-29(15-8-9-16-29)26(37)30-19-21-11-10-14-23(17-21)35-25(18-24(34-35)28(2,3)4)32-27(38)31-22-12-6-5-7-13-22/h5-7,10-14,17-18H,8-9,15-16,19H2,1-4H3,(H,30,37)(H,33,36)(H2,31,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of active p38alpha				Bioorg Med Chem Lett 20: 4885-91 (2010) Article DOI: 10.1016/j.bmcl.2010.06.073 BindingDB Entry DOI: 10.7270/Q2Z31ZT2
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50323422 (1-acetamido-N-(3-(3-tert-butyl-5-(3-phenylureido)-...) Show SMILES CC(=O)NC1(CCCC1)C(=O)NCc1cccc(c1)-n1nc(cc1NC(=O)Nc1ccccc1)C(C)(C)C Show InChI InChI=1S/C29H36N6O3/c1-20(36)33-29(15-8-9-16-29)26(37)30-19-21-11-10-14-23(17-21)35-25(18-24(34-35)28(2,3)4)32-27(38)31-22-12-6-5-7-13-22/h5-7,10-14,17-18H,8-9,15-16,19H2,1-4H3,(H,30,37)(H,33,36)(H2,31,32,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	715	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of unactive p38alpha				Bioorg Med Chem Lett 20: 4885-91 (2010) Article DOI: 10.1016/j.bmcl.2010.06.073 BindingDB Entry DOI: 10.7270/Q2Z31ZT2
					More data for this Ligand-Target Pair