null

SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CN2CCOC2=O)c1

InChI Key: InChIKey=UAMJQKNTOMGFCG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50323426 (CHEMBL1209481 | N-(3-(3-tert-butyl-5-(3-phenylurei...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CN2CCOC2=O)c1 Show InChI InChI=1S/C26H30N6O4/c1-26(2,3)21-15-22(29-24(34)28-19-9-5-4-6-10-19)32(30-21)20-11-7-8-18(14-20)16-27-23(33)17-31-12-13-36-25(31)35/h4-11,14-15H,12-13,16-17H2,1-3H3,(H,27,33)(H2,28,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	599	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of active p38alpha				Bioorg Med Chem Lett 20: 4885-91 (2010) Article DOI: 10.1016/j.bmcl.2010.06.073 BindingDB Entry DOI: 10.7270/Q2Z31ZT2
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50323426 (CHEMBL1209481 | N-(3-(3-tert-butyl-5-(3-phenylurei...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(n1)-c1cccc(CNC(=O)CN2CCOC2=O)c1 Show InChI InChI=1S/C26H30N6O4/c1-26(2,3)21-15-22(29-24(34)28-19-9-5-4-6-10-19)32(30-21)20-11-7-8-18(14-20)16-27-23(33)17-31-12-13-36-25(31)35/h4-11,14-15H,12-13,16-17H2,1-3H3,(H,27,33)(H2,28,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of unactive p38alpha				Bioorg Med Chem Lett 20: 4885-91 (2010) Article DOI: 10.1016/j.bmcl.2010.06.073 BindingDB Entry DOI: 10.7270/Q2Z31ZT2
					More data for this Ligand-Target Pair