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BDBM50323609 (+/-)-N-(2-(3-bromophenyl)-3-(4-chlorophenyl)-2-methylpropyl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide::CHEMBL1209598

SMILES: CC(C)(Oc1ccc(cn1)C(F)(F)F)C(=O)NCC(C)(Cc1ccc(Cl)cc1)c1cccc(Br)c1

InChI Key: InChIKey=SFVUQPBKKWOUKN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323609   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50323609
PNG
((+/-)-N-(2-(3-bromophenyl)-3-(4-chlorophenyl)-2-me...)
Show SMILES CC(C)(Oc1ccc(cn1)C(F)(F)F)C(=O)NCC(C)(Cc1ccc(Cl)cc1)c1cccc(Br)c1
Show InChI InChI=1S/C26H25BrClF3N2O2/c1-24(2,35-22-12-9-19(15-32-22)26(29,30)31)23(34)33-16-25(3,18-5-4-6-20(27)13-18)14-17-7-10-21(28)11-8-17/h4-13,15H,14,16H2,1-3H3,(H,33,34)
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55490 from human recombinant cannabinoid CB1 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4757-61 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.127
BindingDB Entry DOI: 10.7270/Q2NK3F71
More data for this
Ligand-Target Pair