BDBM50323612 (+/-)-1-(3-(4-chlorobenzyl)-3-phenylpyrrolidin-1-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propan-1-one::CHEMBL1209670

SMILES: CC(C)(Oc1ccc(cn1)C(F)(F)F)C(=O)N1CCC(Cc2ccc(Cl)cc2)(C1)c1ccccc1

InChI Key: InChIKey=AHIGFBNAPKVCDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50323612 ((+/-)-1-(3-(4-chlorobenzyl)-3-phenylpyrrolidin-1-y...) Show SMILES CC(C)(Oc1ccc(cn1)C(F)(F)F)C(=O)N1CCC(Cc2ccc(Cl)cc2)(C1)c1ccccc1 Show InChI InChI=1S/C27H26ClF3N2O2/c1-25(2,35-23-13-10-21(17-32-23)27(29,30)31)24(34)33-15-14-26(18-33,20-6-4-3-5-7-20)16-19-8-11-22(28)12-9-19/h3-13,17H,14-16,18H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP55490 from human recombinant cannabinoid CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 4757-61 (2010) Article DOI: 10.1016/j.bmcl.2010.06.127 BindingDB Entry DOI: 10.7270/Q2NK3F71
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