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BDBM50323913 CHEMBL1213785::Tamoxifen isopropyl bromide

SMILES: CC\C(=C(/c1ccccc1)c1ccc(OCC[N+](C)(C)C(C)C)cc1)c1ccccc1

InChI Key: InChIKey=YAWPGHRGMHCVQA-ZIADKAODSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323913   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM50323913
PNG
(CHEMBL1213785 | Tamoxifen isopropyl bromide)
Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCC[N+](C)(C)C(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C29H36NO/c1-6-28(24-13-9-7-10-14-24)29(25-15-11-8-12-16-25)26-17-19-27(20-18-26)31-22-21-30(4,5)23(2)3/h7-20,23H,6,21-22H2,1-5H3/q+1/b29-28-
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 25.4n/an/an/an/an/an/an/an/a



Instituto Politécnico Nacional 2508

Curated by ChEMBL


Assay Description
Displacement of [2,4,6,7-3H]estradiol from human ERalpha expressed in HeLa cells after 18 hrs by liquid scintillation counting

Bioorg Med Chem 18: 5593-601 (2010)


Article DOI: 10.1016/j.bmc.2010.06.039
BindingDB Entry DOI: 10.7270/Q2NG4QT9
More data for this
Ligand-Target Pair