BDBM50323923 (E)-3-((2-(Fluoromethyl)thiazol-4-yl)ethynyl)cyclohex-2-enone O-methyl oxime::CHEMBL1214301

SMILES: CO\N=C1/CCCC(=C1)C#Cc1csc(CF)n1

InChI Key: InChIKey=PQFTVQABLXGQCF-LFIBNONCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50323923 ((E)-3-((2-(Fluoromethyl)thiazol-4-yl)ethynyl)cyclo...) Show SMILES CO\N=C1/CCCC(=C1)C#Cc1csc(CF)n1 |c:7| Show InChI InChI=1S/C13H13FN2OS/c1-17-16-11-4-2-3-10(7-11)5-6-12-9-18-13(8-14)15-12/h7,9H,2-4,8H2,1H3/b16-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ETH Zurich (Swiss Federal Institute of Technology) Curated by ChEMBL					Assay Description Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation counting				Bioorg Med Chem 18: 6044-54 (2010) Article DOI: 10.1016/j.bmc.2010.06.070 BindingDB Entry DOI: 10.7270/Q2862GMS
					More data for this Ligand-Target Pair