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SMILES: CO\N=C1/CCCC(=C1)C#Cc1nccs1

InChI Key: InChIKey=IBFWHZRPCYJYIB-SDNWHVSQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323924   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50323924
PNG
((E)-3-(Thiazol-2-ylethynyl)cyclohex-2-enone O-meth...)
Show SMILES CO\N=C1/CCCC(=C1)C#Cc1nccs1 |c:7|
Show InChI InChI=1S/C12H12N2OS/c1-15-14-11-4-2-3-10(9-11)5-6-12-13-7-8-16-12/h7-9H,2-4H2,1H3/b14-11+
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Article
PubMed
 20.3n/an/an/an/an/an/an/an/a



ETH Zurich (Swiss Federal Institute of Technology)

Curated by ChEMBL


Assay Description
Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation counting

Bioorg Med Chem 18: 6044-54 (2010)


Article DOI: 10.1016/j.bmc.2010.06.070
BindingDB Entry DOI: 10.7270/Q2862GMS
More data for this
Ligand-Target Pair