BDBM50324097 CHEMBL1214831::N-(Benzofuran-2-ylmethyl)-N'-(4'-ethoxybenzyl)piperazine

SMILES: CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1

InChI Key: InChIKey=SARQYPUTTRFHLZ-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50324097 (CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...) Show SMILES CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C22H26N2O2/c1-2-25-20-9-7-18(8-10-20)16-23-11-13-24(14-12-23)17-21-15-19-5-3-4-6-22(19)26-21/h3-10,15H,2,11-14,16-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain homogenate				Bioorg Med Chem Lett 22: 5493-7 (2012) Article DOI: 10.1016/j.bmcl.2012.07.026 BindingDB Entry DOI: 10.7270/Q2FF3TDK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50324097 (CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...) Show SMILES CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C22H26N2O2/c1-2-25-20-9-7-18(8-10-20)16-23-11-13-24(14-12-23)17-21-15-19-5-3-4-6-22(19)26-21/h3-10,15H,2,11-14,16-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenate				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50324097 (CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...) Show SMILES CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C22H26N2O2/c1-2-25-20-9-7-18(8-10-20)16-23-11-13-24(14-12-23)17-21-15-19-5-3-4-6-22(19)26-21/h3-10,15H,2,11-14,16-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	262	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity to 5HT2B				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50324097 (CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...) Show SMILES CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C22H26N2O2/c1-2-25-20-9-7-18(8-10-20)16-23-11-13-24(14-12-23)17-21-15-19-5-3-4-6-22(19)26-21/h3-10,15H,2,11-14,16-17H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity to 5HT1A				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50324097 (CHEMBL1214831 | N-(Benzofuran-2-ylmethyl)-N'-(4'-e...) Show SMILES CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C22H26N2O2/c1-2-25-20-9-7-18(8-10-20)16-23-11-13-24(14-12-23)17-21-15-19-5-3-4-6-22(19)26-21/h3-10,15H,2,11-14,16-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity to dopamine D2				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair