BDBM50324098 CHEMBL1214891::N-(Benzofuran-2-ylmethyl)-N'-(4'-(2''-fluoroethoxy)benzyl)-piperazine

SMILES: FC(F)CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1

InChI Key: InChIKey=WDONHKNAYNXFMH-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50324098 (CHEMBL1214891 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...) Show SMILES FC(F)CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C23H26F2N2O2/c24-23(25)9-14-28-20-7-5-18(6-8-20)16-26-10-12-27(13-11-26)17-21-15-19-3-1-2-4-22(19)29-21/h1-8,15,23H,9-14,16-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenate				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50324098 (CHEMBL1214891 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...) Show SMILES FC(F)CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C23H26F2N2O2/c24-23(25)9-14-28-20-7-5-18(6-8-20)16-26-10-12-27(13-11-26)17-21-15-19-3-1-2-4-22(19)29-21/h1-8,15,23H,9-14,16-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity to 5HT2B				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50324098 (CHEMBL1214891 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...) Show SMILES FC(F)CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C23H26F2N2O2/c24-23(25)9-14-28-20-7-5-18(6-8-20)16-26-10-12-27(13-11-26)17-21-15-19-3-1-2-4-22(19)29-21/h1-8,15,23H,9-14,16-17H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity to 5HT1A				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50324098 (CHEMBL1214891 | N-(Benzofuran-2-ylmethyl)-N'-(4'-(...) Show SMILES FC(F)CCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 Show InChI InChI=1S/C23H26F2N2O2/c24-23(25)9-14-28-20-7-5-18(6-8-20)16-26-10-12-27(13-11-26)17-21-15-19-3-1-2-4-22(19)29-21/h1-8,15,23H,9-14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Binding affinity to dopamine D2				J Med Chem 53: 6228-39 (2010) Article DOI: 10.1021/jm100639f BindingDB Entry DOI: 10.7270/Q2V1250J
					More data for this Ligand-Target Pair