BDBM50324515 6-(aminomethyl)-5-(2,4-dichlorophenyl)-N,N-diethyl-7-methylimidazo[1,2-a]pyrimidine-2-carboxamide::CHEMBL1214877

SMILES: CCN(CC)C(=O)c1cn2c(c(CN)c(C)nc2n1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=SFJZQFDOUQNSBE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50324515 (6-(aminomethyl)-5-(2,4-dichlorophenyl)-N,N-diethyl...) Show SMILES CCN(CC)C(=O)c1cn2c(c(CN)c(C)nc2n1)-c1ccc(Cl)cc1Cl |(-7.06,-1.08,;-6.33,.27,;-4.79,.32,;-3.98,-.99,;-4.71,-2.34,;-4.07,1.68,;-4.88,2.99,;-2.52,1.73,;-1.58,.51,;-.13,1.03,;1.22,.3,;2.53,1.1,;3.89,.38,;5.19,1.19,;2.48,2.65,;3.79,3.47,;1.12,3.37,;-.18,2.56,;-1.66,2.99,;1.19,-1.24,;-.16,-1.98,;-.19,-3.51,;1.13,-4.32,;1.1,-5.86,;2.48,-3.56,;2.5,-2.03,;3.85,-1.28,)| Show InChI InChI=1S/C19H21Cl2N5O/c1-4-25(5-2)18(27)16-10-26-17(13-7-6-12(20)8-15(13)21)14(9-22)11(3)23-19(26)24-16/h6-8,10H,4-5,9,22H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human DPP9				J Med Chem 53: 5620-8 (2010) Article DOI: 10.1021/jm100634a BindingDB Entry DOI: 10.7270/Q2S182PX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50324515 (6-(aminomethyl)-5-(2,4-dichlorophenyl)-N,N-diethyl...) Show SMILES CCN(CC)C(=O)c1cn2c(c(CN)c(C)nc2n1)-c1ccc(Cl)cc1Cl |(-7.06,-1.08,;-6.33,.27,;-4.79,.32,;-3.98,-.99,;-4.71,-2.34,;-4.07,1.68,;-4.88,2.99,;-2.52,1.73,;-1.58,.51,;-.13,1.03,;1.22,.3,;2.53,1.1,;3.89,.38,;5.19,1.19,;2.48,2.65,;3.79,3.47,;1.12,3.37,;-.18,2.56,;-1.66,2.99,;1.19,-1.24,;-.16,-1.98,;-.19,-3.51,;1.13,-4.32,;1.1,-5.86,;2.48,-3.56,;2.5,-2.03,;3.85,-1.28,)| Show InChI InChI=1S/C19H21Cl2N5O/c1-4-25(5-2)18(27)16-10-26-17(13-7-6-12(20)8-15(13)21)14(9-22)11(3)23-19(26)24-16/h6-8,10H,4-5,9,22H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human DPP8				J Med Chem 53: 5620-8 (2010) Article DOI: 10.1021/jm100634a BindingDB Entry DOI: 10.7270/Q2S182PX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50324515 (6-(aminomethyl)-5-(2,4-dichlorophenyl)-N,N-diethyl...) Show SMILES CCN(CC)C(=O)c1cn2c(c(CN)c(C)nc2n1)-c1ccc(Cl)cc1Cl |(-7.06,-1.08,;-6.33,.27,;-4.79,.32,;-3.98,-.99,;-4.71,-2.34,;-4.07,1.68,;-4.88,2.99,;-2.52,1.73,;-1.58,.51,;-.13,1.03,;1.22,.3,;2.53,1.1,;3.89,.38,;5.19,1.19,;2.48,2.65,;3.79,3.47,;1.12,3.37,;-.18,2.56,;-1.66,2.99,;1.19,-1.24,;-.16,-1.98,;-.19,-3.51,;1.13,-4.32,;1.1,-5.86,;2.48,-3.56,;2.5,-2.03,;3.85,-1.28,)| Show InChI InChI=1S/C19H21Cl2N5O/c1-4-25(5-2)18(27)16-10-26-17(13-7-6-12(20)8-15(13)21)14(9-22)11(3)23-19(26)24-16/h6-8,10H,4-5,9,22H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 assessed as Gly-Pro-pNA cleavage				J Med Chem 53: 5620-8 (2010) Article DOI: 10.1021/jm100634a BindingDB Entry DOI: 10.7270/Q2S182PX
					More data for this Ligand-Target Pair