BDBM50324566 2-[4-(1-tert-Butyl-5-methyl-1H-pyrazole-3-carbonyl)piperazin-1-yl]-1-(4-fluorophenyl)ethanone::CHEMBL1214882

SMILES: Cc1cc(nn1C(C)(C)C)C(=O)N1CCN(CC(=O)c2ccc(F)cc2)CC1

InChI Key: InChIKey=JYUUSZZMODAODC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50324566 (2-[4-(1-tert-Butyl-5-methyl-1H-pyrazole-3-carbonyl...) Show SMILES Cc1cc(nn1C(C)(C)C)C(=O)N1CCN(CC(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C21H27FN4O2/c1-15-13-18(23-26(15)21(2,3)4)20(28)25-11-9-24(10-12-25)14-19(27)16-5-7-17(22)8-6-16/h5-8,13H,9-12,14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals. Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293 cells after 1 hr by scintillation counting				J Med Chem 53: 5696-706 (2010) Article DOI: 10.1021/jm100479q BindingDB Entry DOI: 10.7270/Q2CV4HZX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50324566 (2-[4-(1-tert-Butyl-5-methyl-1H-pyrazole-3-carbonyl...) Show SMILES Cc1cc(nn1C(C)(C)C)C(=O)N1CCN(CC(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C21H27FN4O2/c1-15-13-18(23-26(15)21(2,3)4)20(28)25-11-9-24(10-12-25)14-19(27)16-5-7-17(22)8-6-16/h5-8,13H,9-12,14H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals. Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293 cells after 1 hr by scintillation counting				J Med Chem 53: 5696-706 (2010) Article DOI: 10.1021/jm100479q BindingDB Entry DOI: 10.7270/Q2CV4HZX
					More data for this Ligand-Target Pair