BDBM50324596 (S)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)-phenyl)-6-fluoro-1,2,3,4-tetrahydroiso-quinoline-3-carboxamide::CHEMBL1215168

SMILES: CN(C)CCOc1cc(ccc1NC(=O)[C@@H]1Cc2cc(F)ccc2CN1)-c1cn[nH]c1

InChI Key: InChIKey=XVAYRHMEOGCOQX-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50324596 ((S)-N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4...) Show SMILES CN(C)CCOc1cc(ccc1NC(=O)[C@@H]1Cc2cc(F)ccc2CN1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C23H26FN5O2/c1-29(2)7-8-31-22-11-15(18-13-26-27-14-18)4-6-20(22)28-23(30)21-10-17-9-19(24)5-3-16(17)12-25-21/h3-6,9,11,13-14,21,25H,7-8,10,12H2,1-2H3,(H,26,27)(H,28,30)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2				J Med Chem 53: 5727-37 (2010) Article DOI: 10.1021/jm100579r BindingDB Entry DOI: 10.7270/Q2833S8C
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