BDBM50324763 (3R,4R)-N3-(4-chlorophenyl)-1-(cyclopropylmethyl)-N4-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1221791

SMILES: Fc1cc(ccc1NC(=O)[C@H]1CN(CC2CC2)C[C@@H]1C(=O)Nc1ccc(Cl)cc1)-n1ccccc1=O

InChI Key: InChIKey=VQWDOJFHEGVRDZ-VXKWHMMOSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324763 ((3R,4R)-N3-(4-chlorophenyl)-1-(cyclopropylmethyl)-...) Show SMILES Fc1cc(ccc1NC(=O)[C@H]1CN(CC2CC2)C[C@@H]1C(=O)Nc1ccc(Cl)cc1)-n1ccccc1=O |r| Show InChI InChI=1S/C27H26ClFN4O3/c28-18-6-8-19(9-7-18)30-26(35)21-15-32(14-17-4-5-17)16-22(21)27(36)31-24-11-10-20(13-23(24)29)33-12-2-1-3-25(33)34/h1-3,6-13,17,21-22H,4-5,14-16H2,(H,30,35)(H,31,36)/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50324763 ((3R,4R)-N3-(4-chlorophenyl)-1-(cyclopropylmethyl)-...) Show SMILES Fc1cc(ccc1NC(=O)[C@H]1CN(CC2CC2)C[C@@H]1C(=O)Nc1ccc(Cl)cc1)-n1ccccc1=O |r| Show InChI InChI=1S/C27H26ClFN4O3/c28-18-6-8-19(9-7-18)30-26(35)21-15-32(14-17-4-5-17)16-22(21)27(36)31-24-11-10-20(13-23(24)29)33-12-2-1-3-25(33)34/h1-3,6-13,17,21-22H,4-5,14-16H2,(H,30,35)(H,31,36)/t21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair