BDBM50324767 (3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-1-(thiophen-2-ylmethyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1221849

SMILES: Fc1cc(ccc1NC(=O)[C@H]1CN(Cc2cccs2)C[C@@H]1C(=O)Nc1ccc(Cl)cc1)-n1ccccc1=O

InChI Key: InChIKey=ADEJRCDYIZQEHV-GOTSBHOMSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324767 ((3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(2-oxop...) Show SMILES Fc1cc(ccc1NC(=O)[C@H]1CN(Cc2cccs2)C[C@@H]1C(=O)Nc1ccc(Cl)cc1)-n1ccccc1=O |r| Show InChI InChI=1S/C28H24ClFN4O3S/c29-18-6-8-19(9-7-18)31-27(36)22-16-33(15-21-4-3-13-38-21)17-23(22)28(37)32-25-11-10-20(14-24(25)30)34-12-2-1-5-26(34)35/h1-14,22-23H,15-17H2,(H,31,36)(H,32,37)/t22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50324767 ((3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(2-oxop...) Show SMILES Fc1cc(ccc1NC(=O)[C@H]1CN(Cc2cccs2)C[C@@H]1C(=O)Nc1ccc(Cl)cc1)-n1ccccc1=O |r| Show InChI InChI=1S/C28H24ClFN4O3S/c29-18-6-8-19(9-7-18)31-27(36)22-16-33(15-21-4-3-13-38-21)17-23(22)28(37)32-25-11-10-20(14-24(25)30)34-12-2-1-5-26(34)35/h1-14,22-23H,15-17H2,(H,31,36)(H,32,37)/t22-,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair