BDBM50324788 (3R,4R)-N3-(4-chlorophenyl)-1-(methylsulfonyl)-N4-(5-(2-(methylsulfonyl)phenyl)pyridin-2-yl)pyrrolidine-3,4-dicarboxamide::CHEMBL1222342

SMILES: CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cn1)-c1ccccc1S(C)(=O)=O)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=DNNWQTGLEBYPRK-SFTDATJTSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324788 ((3R,4R)-N3-(4-chlorophenyl)-1-(methylsulfonyl)-N4-...) Show SMILES CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cn1)-c1ccccc1S(C)(=O)=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C25H25ClN4O6S2/c1-37(33,34)22-6-4-3-5-19(22)16-7-12-23(27-13-16)29-25(32)21-15-30(38(2,35)36)14-20(21)24(31)28-18-10-8-17(26)9-11-18/h3-13,20-21H,14-15H2,1-2H3,(H,28,31)(H,27,29,32)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair