BDBM50324790 (3R,4R)-N3-(4-chlorophenyl)-N4-(3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl)-1-(methylsulfonyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1222344

SMILES: CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-c1ccccc1S(C)(=O)=O)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=RGIKQMZOIDTLMK-SFTDATJTSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324790 ((3R,4R)-N3-(4-chlorophenyl)-N4-(3-fluoro-2'-(methy...) Show SMILES CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-c1ccccc1S(C)(=O)=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H25ClFN3O6S2/c1-38(34,35)24-6-4-3-5-19(24)16-7-12-23(22(28)13-16)30-26(33)21-15-31(39(2,36)37)14-20(21)25(32)29-18-10-8-17(27)9-11-18/h3-13,20-21H,14-15H2,1-2H3,(H,29,32)(H,30,33)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair