BDBM50324793 (3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(3-oxomorpholino)phenyl)-1-(methylsulfonyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1221490

SMILES: CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)N1CCOCC1=O)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=VNSXBTWIXQCLCC-ROUUACIJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324793 ((3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(3-oxom...) Show SMILES CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)N1CCOCC1=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H24ClFN4O6S/c1-36(33,34)28-11-17(22(31)26-15-4-2-14(24)3-5-15)18(12-28)23(32)27-20-7-6-16(10-19(20)25)29-8-9-35-13-21(29)30/h2-7,10,17-18H,8-9,11-13H2,1H3,(H,26,31)(H,27,32)/t17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair