BDBM50324858 1-benzoyl-2-tert-butyldimethylsilyllycorine::CHEMBL1221975

SMILES: CC(C)(C)[Si](C)(C)O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H]([C@@H]23)[C@@H]1OC(=O)c1ccccc1

InChI Key: InChIKey=FPFREWZKIINHID-GWMMUDDPSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM50324858 (1-benzoyl-2-tert-butyldimethylsilyllycorine | CHEM...) Show SMILES CC(C)(C)[Si](C)(C)O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H]([C@@H]23)[C@@H]1OC(=O)c1ccccc1 |r,t:9| Show InChI InChI=1S/C29H35NO5Si/c1-29(2,3)36(4,5)35-24-13-19-11-12-30-16-20-14-22-23(33-17-32-22)15-21(20)25(26(19)30)27(24)34-28(31)18-9-7-6-8-10-18/h6-10,13-15,24-27H,11-12,16-17H2,1-5H3/t24-,25-,26+,27+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McMaster University Curated by ChEMBL					Assay Description Inhibition of AChE by Ellman's assay				Bioorg Med Chem Lett 20: 5290-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.130 BindingDB Entry DOI: 10.7270/Q2CN7437
					More data for this Ligand-Target Pair