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BDBM50324985 CHEMBL1221459::N-[5-(3-Methyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-thiazol-2-yl]-benzamide

SMILES: Cc1noc(n1)-c1sc(NC(=O)c2ccccc2)nc1-c1ccccc1

InChI Key: InChIKey=VXICBIKGZNYPSZ-UHFFFAOYSA-N

Data: 2 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324985   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Homo sapiens (Human))
BDBM50324985
PNG
(CHEMBL1221459 | N-[5-(3-Methyl-[1,2,4]oxadiazol-5-...)
Show SMILES Cc1noc(n1)-c1sc(NC(=O)c2ccccc2)nc1-c1ccccc1
Show InChI InChI=1S/C19H14N4O2S/c1-12-20-18(25-23-12)16-15(13-8-4-2-5-9-13)21-19(26-16)22-17(24)14-10-6-3-7-11-14/h2-11H,1H3,(H,21,22,24)
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PC sid
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Article
PubMed
180n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells by liquid scintillation counting


Bioorg Med Chem Lett 20: 5241-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.138
BindingDB Entry DOI: 10.7270/Q2BP02Z0
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))
BDBM50324985
PNG
(CHEMBL1221459 | N-[5-(3-Methyl-[1,2,4]oxadiazol-5-...)
Show SMILES Cc1noc(n1)-c1sc(NC(=O)c2ccccc2)nc1-c1ccccc1
Show InChI InChI=1S/C19H14N4O2S/c1-12-20-18(25-23-12)16-15(13-8-4-2-5-9-13)21-19(26-16)22-17(24)14-10-6-3-7-11-14/h2-11H,1H3,(H,21,22,24)
PDB
MMDB

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UniChem

Patents

Article
PubMed
190n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in buculovirus system by liquid scintillation counting


Bioorg Med Chem Lett 20: 5241-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.138
BindingDB Entry DOI: 10.7270/Q2BP02Z0
More data for this
Ligand-Target Pair