BDBM50325047 1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl)-4-methyl-1,4-diazepane::CHEMBL1222871

SMILES: CN1CCCN(CC1)C(c1nnnn1Cc1ccccc1)c1ccc(F)cc1

InChI Key: InChIKey=PGNIUXGQLVHGHX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325047 (1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)meth...) Show SMILES CN1CCCN(CC1)C(c1nnnn1Cc1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C21H25FN6/c1-26-12-5-13-27(15-14-26)20(18-8-10-19(22)11-9-18)21-23-24-25-28(21)16-17-6-3-2-4-7-17/h2-4,6-11,20H,5,12-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	738	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair