BDBM50325050 1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl)-4-cyclopentyl-1,4-diazepane::CHEMBL1222945

SMILES: Fc1ccc(cc1)C(N1CCCN(CC1)C1CCCC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=JPKXYHFSWDFHJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325050 (1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)meth...) Show SMILES Fc1ccc(cc1)C(N1CCCN(CC1)C1CCCC1)c1nnnn1Cc1ccccc1 Show InChI InChI=1S/C25H31FN6/c26-22-13-11-21(12-14-22)24(25-27-28-29-32(25)19-20-7-2-1-3-8-20)31-16-6-15-30(17-18-31)23-9-4-5-10-23/h1-3,7-8,11-14,23-24H,4-6,9-10,15-19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair