BDBM50325054 (1S,4S)-2-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl)-5-cyclobutyl-2,5-diazabicyclo[2.2.1]heptane::CHEMBL1223008

SMILES: Fc1ccc(cc1)C(N1C[C@@H]2C[C@H]1CN2C1CCC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=QJZHGLMHUFXFNJ-OJSMNCEXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325054 ((1S,4S)-2-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophe...) Show SMILES Fc1ccc(cc1)C(N1C[C@@H]2C[C@H]1CN2C1CCC1)c1nnnn1Cc1ccccc1 |r| Show InChI InChI=1S/C24H27FN6/c25-19-11-9-18(10-12-19)23(24-26-27-28-31(24)14-17-5-2-1-3-6-17)30-16-21-13-22(30)15-29(21)20-7-4-8-20/h1-3,5-6,9-12,20-23H,4,7-8,13-16H2/t21-,22-,23?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair