BDBM50325058 7-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine::CHEMBL1223079

SMILES: Fc1ccc(cc1)C(N1CCn2cnnc2C1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=UPAVVBVOLKJIJO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325058 (7-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)meth...) Show SMILES Fc1ccc(cc1)C(N1CCn2cnnc2C1)c1nnnn1Cc1ccccc1 Show InChI InChI=1S/C20H19FN8/c21-17-8-6-16(7-9-17)19(27-10-11-28-14-22-23-18(28)13-27)20-24-25-26-29(20)12-15-4-2-1-3-5-15/h1-9,14,19H,10-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair