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BDBM50325060 1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl)-4-(pyrrolidin-1-yl)piperidine::CHEMBL1223081

SMILES: Fc1ccc(cc1)C(N1CCC(CC1)N1CCCC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=OCTOTSFTKODCCC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325060   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50325060
PNG
(1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)meth...)
Show SMILES Fc1ccc(cc1)C(N1CCC(CC1)N1CCCC1)c1nnnn1Cc1ccccc1
Show InChI InChI=1S/C24H29FN6/c25-21-10-8-20(9-11-21)23(30-16-12-22(13-17-30)29-14-4-5-15-29)24-26-27-28-31(24)18-19-6-2-1-3-7-19/h1-3,6-11,22-23H,4-5,12-18H2
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.43E+3n/an/an/an/an/an/a



Evotec (UK) Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor


Bioorg Med Chem Lett 20: 5165-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.009
BindingDB Entry DOI: 10.7270/Q2TQ61RV
More data for this
Ligand-Target Pair