BDBM50325062 1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl)-4-(1-methylpiperidin-4-yl)piperazine::CHEMBL1223156

SMILES: CN1CCC(CC1)N1CCN(CC1)C(c1nnnn1Cc1ccccc1)c1ccc(F)cc1

InChI Key: InChIKey=SKMWDKKKIZNIEI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325062 (1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)meth...) Show SMILES CN1CCC(CC1)N1CCN(CC1)C(c1nnnn1Cc1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C25H32FN7/c1-30-13-11-23(12-14-30)31-15-17-32(18-16-31)24(21-7-9-22(26)10-8-21)25-27-28-29-33(25)19-20-5-3-2-4-6-20/h2-10,23-24H,11-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair