BDBM50325083 1-(4-((1-benzyl-1H-tetrazol-5-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methyl)phenyl)pyrrolidin-2-one::CHEMBL1223514

SMILES: O=C1CCCN1c1ccc(cc1)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=IDVJJPKAQVFLME-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325083 (1-(4-((1-benzyl-1H-tetrazol-5-yl)(4-cyclobutyl-1,4...) Show SMILES O=C1CCCN1c1ccc(cc1)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1 Show InChI InChI=1S/C28H35N7O/c36-26-11-5-18-34(26)25-14-12-23(13-15-25)27(33-17-6-16-32(19-20-33)24-9-4-10-24)28-29-30-31-35(28)21-22-7-2-1-3-8-22/h1-3,7-8,12-15,24,27H,4-6,9-11,16-21H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair