BDBM50325098 1-((1-benzyl-1H-tetrazol-5-yl)(2,3-dihydrobenzofuran-5-yl)methyl)-4-cyclobutyl-1,4-diazepane::CHEMBL1221424

SMILES: C(c1ccccc1)n1nnnc1C(N1CCCN(CC1)C1CCC1)c1ccc2OCCc2c1

InChI Key: InChIKey=NGQFJHWTJYXDMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325098 (1-((1-benzyl-1H-tetrazol-5-yl)(2,3-dihydrobenzofur...) Show SMILES C(c1ccccc1)n1nnnc1C(N1CCCN(CC1)C1CCC1)c1ccc2OCCc2c1 Show InChI InChI=1S/C26H32N6O/c1-2-6-20(7-3-1)19-32-26(27-28-29-32)25(22-10-11-24-21(18-22)12-17-33-24)31-14-5-13-30(15-16-31)23-8-4-9-23/h1-3,6-7,10-11,18,23,25H,4-5,8-9,12-17,19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58.5	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair