BDBM50325102 5-((1-benzyl-1H-tetrazol-5-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methyl)-1-methyl-1H-benzo[d][1,2,3]triazole::CHEMBL1222729

SMILES: Cn1nnc2cc(ccc12)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=UNOBLPOTLFGCTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325102 (5-((1-benzyl-1H-tetrazol-5-yl)(4-cyclobutyl-1,4-di...) Show SMILES Cn1nnc2cc(ccc12)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1 Show InChI InChI=1S/C25H31N9/c1-31-23-12-11-20(17-22(23)26-29-31)24(33-14-6-13-32(15-16-33)21-9-5-10-21)25-27-28-30-34(25)18-19-7-3-2-4-8-19/h2-4,7-8,11-12,17,21,24H,5-6,9-10,13-16,18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair