BDBM50325489 1-butyl-4-isopropyl-2-(4-isopropylphenyl)-1H-benzo[d]imidazole::CHEMBL1223221

SMILES: CCCCn1c(nc2c(cccc12)C(C)C)-c1ccc(cc1)C(C)C

InChI Key: InChIKey=MOXNEMZQUOGGGH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325489 (1-butyl-4-isopropyl-2-(4-isopropylphenyl)-1H-benzo...) Show SMILES CCCCn1c(nc2c(cccc12)C(C)C)-c1ccc(cc1)C(C)C Show InChI InChI=1S/C23H30N2/c1-6-7-15-25-21-10-8-9-20(17(4)5)22(21)24-23(25)19-13-11-18(12-14-19)16(2)3/h8-14,16-17H,6-7,15H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization				Bioorg Med Chem Lett 20: 5161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.016 BindingDB Entry DOI: 10.7270/Q2H70G1X
					More data for this Ligand-Target Pair