BDBM50325506 2-(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1H-benzo[d]imidazol-1-yl)-N,N-dimethylacetamide::CHEMBL1223441

SMILES: COc1ccc(Br)c2nc(-c3ccc(cc3)C(C)C)n(CC(=O)N(C)C)c12

InChI Key: InChIKey=KNMAUMNVOMJGPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325506 (2-(4-bromo-2-(4-isopropylphenyl)-7-methoxy-1H-benz...) Show SMILES COc1ccc(Br)c2nc(-c3ccc(cc3)C(C)C)n(CC(=O)N(C)C)c12 Show InChI InChI=1S/C21H24BrN3O2/c1-13(2)14-6-8-15(9-7-14)21-23-19-16(22)10-11-17(27-5)20(19)25(21)12-18(26)24(3)4/h6-11,13H,12H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization				Bioorg Med Chem Lett 20: 5161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.016 BindingDB Entry DOI: 10.7270/Q2H70G1X
					More data for this Ligand-Target Pair