BDBM50325514 4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)-5-phenyl-1H-benzo[d]imidazole::CHEMBL1222426

SMILES: COCCn1c(nc2c(Br)c(cc(OC)c12)-c1ccccc1)-c1ccc(cc1)C(C)C

InChI Key: InChIKey=VPQCBKGIBDARNR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325514 (4-bromo-2-(4-isopropylphenyl)-7-methoxy-1-(2-metho...) Show SMILES COCCn1c(nc2c(Br)c(cc(OC)c12)-c1ccccc1)-c1ccc(cc1)C(C)C Show InChI InChI=1S/C26H27BrN2O2/c1-17(2)18-10-12-20(13-11-18)26-28-24-23(27)21(19-8-6-5-7-9-19)16-22(31-4)25(24)29(26)14-15-30-3/h5-13,16-17H,14-15H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization				Bioorg Med Chem Lett 20: 5161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.016 BindingDB Entry DOI: 10.7270/Q2H70G1X
					More data for this Ligand-Target Pair