BDBM50325518 4-bromo-5-(3,4-dimethylbenzyl)-2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)-1H-benzo[d]imidazole::CHEMBL1222491

SMILES: COCCn1c(nc2c(Br)c(Cc3ccc(C)c(C)c3)cc(OC)c12)-c1ccc(cc1)C(C)C

InChI Key: InChIKey=YRHWAFSPOLEYIJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325518 (4-bromo-5-(3,4-dimethylbenzyl)-2-(4-isopropylpheny...) Show SMILES COCCn1c(nc2c(Br)c(Cc3ccc(C)c(C)c3)cc(OC)c12)-c1ccc(cc1)C(C)C Show InChI InChI=1S/C29H33BrN2O2/c1-18(2)22-9-11-23(12-10-22)29-31-27-26(30)24(16-21-8-7-19(3)20(4)15-21)17-25(34-6)28(27)32(29)13-14-33-5/h7-12,15,17-18H,13-14,16H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization				Bioorg Med Chem Lett 20: 5161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.016 BindingDB Entry DOI: 10.7270/Q2H70G1X
					More data for this Ligand-Target Pair