BDBM50325790 CHEMBL1224717::methyl 2-(4-((8-(3-methoxyphenyl)quinolin-6-yl)methoxy)phenyl)acetate

SMILES: COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1

InChI Key: InChIKey=DOKUUHZWXPIFPB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50325790 (CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...) Show SMILES COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1 Show InChI InChI=1S/C26H23NO4/c1-29-23-7-3-5-20(16-23)24-14-19(13-21-6-4-12-27-26(21)24)17-31-22-10-8-18(9-11-22)15-25(28)30-2/h3-14,16H,15,17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human PDE4C				Bioorg Med Chem Lett 20: 5502-5 (2010) Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ
					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50325790 (CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...) Show SMILES COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1 Show InChI InChI=1S/C26H23NO4/c1-29-23-7-3-5-20(16-23)24-14-19(13-21-6-4-12-27-26(21)24)17-31-22-10-8-18(9-11-22)15-25(28)30-2/h3-14,16H,15,17H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human PDE4B				Bioorg Med Chem Lett 20: 5502-5 (2010) Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50325790 (CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...) Show SMILES COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1 Show InChI InChI=1S/C26H23NO4/c1-29-23-7-3-5-20(16-23)24-14-19(13-21-6-4-12-27-26(21)24)17-31-22-10-8-18(9-11-22)15-25(28)30-2/h3-14,16H,15,17H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human PDE4A				Bioorg Med Chem Lett 20: 5502-5 (2010) Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50325790 (CHEMBL1224717 | methyl 2-(4-((8-(3-methoxyphenyl)q...) Show SMILES COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1 Show InChI InChI=1S/C26H23NO4/c1-29-23-7-3-5-20(16-23)24-14-19(13-21-6-4-12-27-26(21)24)17-31-22-10-8-18(9-11-22)15-25(28)30-2/h3-14,16H,15,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human PDE4D				Bioorg Med Chem Lett 20: 5502-5 (2010) Article DOI: 10.1016/j.bmcl.2010.07.076 BindingDB Entry DOI: 10.7270/Q2K35TVZ
					More data for this Ligand-Target Pair