BDBM50325824 1H-purine-2,6,8(3H,7H,9H)-trione::7,9-Dihydro-3H-purine-2,6,8-trione::7,9-Dihydro-3H-purine-2,6,8-trione(Urate)::7,9-Dihydro-3H-purine-2,6,8-trione(uric acid)::CHEMBL792::URIC ACID

SMILES: O=c1[nH]c2[nH]c(=O)[nH]c(=O)c2[nH]1

InChI Key: InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N

Data: 2 KI

PDB links: 23 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanine deaminase (Homo sapiens (Human))	BDBM50325824 (1H-purine-2,6,8(3H,7H,9H)-trione | 7,9-Dihydro-3H-...) Show SMILES O=c1[nH]c2[nH]c(=O)[nH]c(=O)c2[nH]1 Show InChI InChI=1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New Jersey Curated by ChEMBL					Assay Description Inhibition of GDA by colorimetric assay				Bioorg Med Chem 18: 6748-55 (2010) Article DOI: 10.1016/j.bmc.2010.07.054 BindingDB Entry DOI: 10.7270/Q25T3KPK
					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50325824 (1H-purine-2,6,8(3H,7H,9H)-trione | 7,9-Dihydro-3H-...) Show SMILES O=c1[nH]c2[nH]c(=O)[nH]c(=O)c2[nH]1 Show InChI InChI=1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.75E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georg-August-Universit£t Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Estrone sulfate in Xenopus laevis oocytes				Cell Physiol Biochem 13: 249-56 (2003) Article DOI: 74539 BindingDB Entry DOI: 10.7270/Q2MS3V12
					More data for this Ligand-Target Pair