BDBM50325878 CHEMBL1224213::endo-2-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-yloxy)benzamide

SMILES: NC(=O)c1ccccc1O[C@@H]1C[C@@H]2CC[C@H](C1)N2Cc1ccccc1

InChI Key: InChIKey=VZUNLOUVARCFRX-PIIMJCKOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50325878 (CHEMBL1224213 | endo-2-((1R,5S)-8-benzyl-8-azabicy...) Show SMILES NC(=O)c1ccccc1O[C@@H]1C[C@@H]2CC[C@H](C1)N2Cc1ccccc1 |r,TLB:18:17:14.13:16.10.11| Show InChI InChI=1S/C21H24N2O2/c22-21(24)19-8-4-5-9-20(19)25-18-12-16-10-11-17(13-18)23(16)14-15-6-2-1-3-7-15/h1-9,16-18H,10-14H2,(H2,22,24)/t16-,17+,18+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human kappa opioid receptor expressed in HEK cells assessed as inhibition of dynorphin A-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5405-10 (2010) Article DOI: 10.1016/j.bmcl.2010.07.112 BindingDB Entry DOI: 10.7270/Q2X92BHQ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50325878 (CHEMBL1224213 | endo-2-((1R,5S)-8-benzyl-8-azabicy...) Show SMILES NC(=O)c1ccccc1O[C@@H]1C[C@@H]2CC[C@H](C1)N2Cc1ccccc1 |r,TLB:18:17:14.13:16.10.11| Show InChI InChI=1S/C21H24N2O2/c22-21(24)19-8-4-5-9-20(19)25-18-12-16-10-11-17(13-18)23(16)14-15-6-2-1-3-7-15/h1-9,16-18H,10-14H2,(H2,22,24)/t16-,17+,18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ERG by electrophysiology assay				Bioorg Med Chem Lett 20: 5405-10 (2010) Article DOI: 10.1016/j.bmcl.2010.07.112 BindingDB Entry DOI: 10.7270/Q2X92BHQ
					More data for this Ligand-Target Pair