BDBM50325889 CHEMBL1224535::N-(1-((6-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)methyl)-1H-indol-6-yl)-3-hydroxy-2,2-dimethylpropanamide

SMILES: COc1cc(F)ccc1-c1cccc(Cn2ccc3ccc(NC(=O)C(C)(C)CO)cc23)n1

InChI Key: InChIKey=KVEBRGSWEKDCPX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50325889 (CHEMBL1224535 | N-(1-((6-(4-fluoro-2-methoxyphenyl...) Show SMILES COc1cc(F)ccc1-c1cccc(Cn2ccc3ccc(NC(=O)C(C)(C)CO)cc23)n1 Show InChI InChI=1S/C26H26FN3O3/c1-26(2,16-31)25(32)29-19-9-7-17-11-12-30(23(17)14-19)15-20-5-4-6-22(28-20)21-10-8-18(27)13-24(21)33-3/h4-14,31H,15-16H2,1-3H3,(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]CC55940 human cannabinoid CB1 receptor expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 5449-53 (2010) Article DOI: 10.1016/j.bmcl.2010.07.091 BindingDB Entry DOI: 10.7270/Q2SN0958
					More data for this Ligand-Target Pair