BDBM50325893 CHEMBL1224614::N-(3-((6-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)methyl)-1-methyl-1H-indol-5-yl)-3-hydroxy-2,2-dimethylpropanamide

SMILES: COc1cc(F)ccc1-c1cccc(Cc2cn(C)c3ccc(NC(=O)C(C)(C)CO)cc23)n1

InChI Key: InChIKey=IADFNAUQPCDFOU-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50325893 (CHEMBL1224614 | N-(3-((6-(4-fluoro-2-methoxyphenyl...) Show SMILES COc1cc(F)ccc1-c1cccc(Cc2cn(C)c3ccc(NC(=O)C(C)(C)CO)cc23)n1 Show InChI InChI=1S/C27H28FN3O3/c1-27(2,16-32)26(33)30-20-9-11-24-22(14-20)17(15-31(24)3)12-19-6-5-7-23(29-19)21-10-8-18(28)13-25(21)34-4/h5-11,13-15,32H,12,16H2,1-4H3,(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]CC55940 human cannabinoid CB1 receptor expressed in CHO cells by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 5449-53 (2010) Article DOI: 10.1016/j.bmcl.2010.07.091 BindingDB Entry DOI: 10.7270/Q2SN0958
					More data for this Ligand-Target Pair