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BDBM50326007 4,4'-(naphthalen-2-ylazanediyl)bis(methylene)dibenzene-1,2-diol::CHEMBL1241670

SMILES: Oc1ccc(CN(Cc2ccc(O)c(O)c2)c2ccc3ccccc3c2)cc1O

InChI Key: InChIKey=DSKAWOIEDKIVGD-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326007   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor I receptor


(Homo sapiens (Human))
BDBM50326007
PNG
(4,4'-(naphthalen-2-ylazanediyl)bis(methylene)diben...)
Show SMILES Oc1ccc(CN(Cc2ccc(O)c(O)c2)c2ccc3ccccc3c2)cc1O
Show InChI InChI=1S/C24H21NO4/c26-21-9-5-16(11-23(21)28)14-25(15-17-6-10-22(27)24(29)12-17)20-8-7-18-3-1-2-4-19(18)13-20/h1-13,26-29H,14-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.45E+3n/an/an/an/an/an/a



The Hebrew University of Jerusalem

Curated by ChEMBL


Assay Description
Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISA


Eur J Pharmacol 562: 1-11 (2007)


Article DOI: 10.1016/j.ejphar.2007.01.052
BindingDB Entry DOI: 10.7270/Q2VD6ZPB
More data for this
Ligand-Target Pair
Insulin receptor


(Homo sapiens (Human))
BDBM50326007
PNG
(4,4'-(naphthalen-2-ylazanediyl)bis(methylene)diben...)
Show SMILES Oc1ccc(CN(Cc2ccc(O)c(O)c2)c2ccc3ccccc3c2)cc1O
Show InChI InChI=1S/C24H21NO4/c26-21-9-5-16(11-23(21)28)14-25(15-17-6-10-22(27)24(29)12-17)20-8-7-18-3-1-2-4-19(18)13-20/h1-13,26-29H,14-15H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



The Hebrew University of Jerusalem

Curated by ChEMBL


Assay Description
Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISA


Eur J Pharmacol 562: 1-11 (2007)


Article DOI: 10.1016/j.ejphar.2007.01.052
BindingDB Entry DOI: 10.7270/Q2VD6ZPB
More data for this
Ligand-Target Pair