BDBM50326009 5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-one::CHEMBL1240928

SMILES: Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12

InChI Key: InChIKey=TZUYDLKHNQUNKS-UHFFFAOYSA-N

Data: 1 IC50  5 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50326009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of MYLK				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation ...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spec...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Binding affinity recombinant HuR RRM1/RRM2 domain by confocal fluctuation spectroscopy				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI InChI=1S/C13H10O4/c1-6-11-7(5-17-6)4-8-9(14)2-3-10(15)12(8)13(11)16/h2-3,5,14-15H,4H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spe...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair