BDBM50326113 1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyridinesulfonamide::CHEMBL1242706

SMILES: NS(=O)(=O)c1cn(CC(=O)c2ccc(Cl)c(Cl)c2)ccc1=O

InChI Key: InChIKey=MDABKLUMWAFTGF-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50326113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50326113 (1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...) Show SMILES NS(=O)(=O)c1cn(CC(=O)c2ccc(Cl)c(Cl)c2)ccc1=O Show InChI InChI=1S/C13H10Cl2N2O4S/c14-9-2-1-8(5-10(9)15)12(19)6-17-4-3-11(18)13(7-17)22(16,20)21/h1-5,7H,6H2,(H2,16,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned catalytic domain of CA9 after 15 mins by stopped-flow CO2 hydration assay				Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50326113 (1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...) Show SMILES NS(=O)(=O)c1cn(CC(=O)c2ccc(Cl)c(Cl)c2)ccc1=O Show InChI InChI=1S/C13H10Cl2N2O4S/c14-9-2-1-8(5-10(9)15)12(19)6-17-4-3-11(18)13(7-17)22(16,20)21/h1-5,7H,6H2,(H2,16,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assay				Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50326113 (1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...) Show SMILES NS(=O)(=O)c1cn(CC(=O)c2ccc(Cl)c(Cl)c2)ccc1=O Show InChI InChI=1S/C13H10Cl2N2O4S/c14-9-2-1-8(5-10(9)15)12(19)6-17-4-3-11(18)13(7-17)22(16,20)21/h1-5,7H,6H2,(H2,16,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assay				Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50326113 (1-(3,4-Dichlorophenacyl)-1,4-dihydro-4-oxo-3-pyrid...) Show SMILES NS(=O)(=O)c1cn(CC(=O)c2ccc(Cl)c(Cl)c2)ccc1=O Show InChI InChI=1S/C13H10Cl2N2O4S/c14-9-2-1-8(5-10(9)15)12(19)6-17-4-3-11(18)13(7-17)22(16,20)21/h1-5,7H,6H2,(H2,16,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned CA1 after 15 mins by stopped-flow CO2 hydration assay				Eur J Med Chem 45: 3656-61 (2010) Article DOI: 10.1016/j.ejmech.2010.05.011 BindingDB Entry DOI: 10.7270/Q2SF2WCP
					More data for this Ligand-Target Pair