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SMILES: COc1ccc2-c3cnc4ccccc4c3C(=O)c2c1

InChI Key: InChIKey=WFPHUOKCFAUCHQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326188   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50326188
PNG
(9-Methoxy-11H-indeno[1,2-c]quinolin-11-one | CHEMB...)
Show SMILES COc1ccc2-c3cnc4ccccc4c3C(=O)c2c1
Show InChI InChI=1S/C17H11NO2/c1-20-10-6-7-11-13(8-10)17(19)16-12-4-2-3-5-15(12)18-9-14(11)16/h2-9H,1H3
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresis

J Med Chem 53: 6164-79 (2010)


Article DOI: 10.1021/jm1005447
BindingDB Entry DOI: 10.7270/Q2BZ6710
More data for this
Ligand-Target Pair