BDBM50326231 CHEMBL1242951::N-{1-[3-(6,7-Difluoro-2-oxo-3,4-dihydro-2H-quinolin-1-yl)-propyl]-piperidin-4-yl}-2-phenyl-acetamide

SMILES: Fc1cc2CCC(=O)N(CCCN3CCC(CC3)NC(=O)Cc3ccccc3)c2cc1F

InChI Key: InChIKey=UXVSPVZNGAZNRZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50326231 (CHEMBL1242951 | N-{1-[3-(6,7-Difluoro-2-oxo-3,4-di...) Show SMILES Fc1cc2CCC(=O)N(CCCN3CCC(CC3)NC(=O)Cc3ccccc3)c2cc1F Show InChI InChI=1S/C25H29F2N3O2/c26-21-16-19-7-8-25(32)30(23(19)17-22(21)27)12-4-11-29-13-9-20(10-14-29)28-24(31)15-18-5-2-1-3-6-18/h1-3,5-6,16-17,20H,4,7-15H2,(H,28,31)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay				J Med Chem 53: 6386-97 (2010) Article DOI: 10.1021/jm100697g BindingDB Entry DOI: 10.7270/Q2765G9K
					More data for this Ligand-Target Pair