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BDBM50326244 CHEMBL1243202::N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propyl]-piperidin-4-yl}-acetamide

SMILES: CC(=O)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1

InChI Key: InChIKey=DMIMQUNGRKPUHD-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326244   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326244
PNG
(CHEMBL1243202 | N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1...)
Show SMILES CC(=O)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1
Show InChI InChI=1S/C18H25N3O3/c1-14(22)19-15-7-11-20(12-8-15)9-4-10-21-16-5-2-3-6-17(16)24-13-18(21)23/h2-3,5-6,15H,4,7-13H2,1H3,(H,19,22)
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UniProtKB/TrEMBL

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Article
PubMed
n/an/an/an/a 180n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair