BindingDB PrimarySearch

BDBM50326325 1-(2-chloro-4-nitrobenzyl)-4-(benzyloxy)pyridin-2(1H)-one::4-(benzyloxy)-1-(2-chloro-4-nitrobenzyl)pyridin-2(1H)-one::CHEMBL260771

SMILES: [O-][N+](=O)c1ccc(Cn2ccc(OCc3ccccc3)cc2=O)c(Cl)c1

InChI Key: InChIKey=RIQOGTFTKRBIMQ-UHFFFAOYSA-N

Data: 2 IC50

Found 2 hits for monomerid = 50326325
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Enoyl-[acyl-carrier-protein] reductase [NADH] (Bacillus subtilis (strain 168))	BDBM50326325 (1-(2-chloro-4-nitrobenzyl)-4-(benzyloxy)pyridin-2(...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis Enoyl ACP reductase				Bioorg Med Chem Lett 18: 3565-9 (2008) Article DOI: 10.1016/j.bmcl.2008.05.004 BindingDB Entry DOI: 10.7270/Q2668F39
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase (Toxoplasma gondii)	BDBM50326325 (1-(2-chloro-4-nitrobenzyl)-4-(benzyloxy)pyridin-2(...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase				J Med Chem 53: 6287-300 (2010) Article DOI: 10.1021/jm9017724 BindingDB Entry DOI: 10.7270/Q2B858CM
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair