BDBM50326438 9-trifluoromethyl-1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde::CHEMBL1243129

SMILES: FC(F)(F)c1cccc2c1[nH]c1c2ccc2c(C=O)c[nH]c12

InChI Key: InChIKey=SHXZNKIVNYEJBF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50326438 (9-trifluoromethyl-1,10-dihydropyrrolo[2,3-a]carbaz...) Show SMILES FC(F)(F)c1cccc2c1[nH]c1c2ccc2c(C=O)c[nH]c12 Show InChI InChI=1S/C16H9F3N2O/c17-16(18,19)12-3-1-2-10-11-5-4-9-8(7-22)6-20-14(9)15(11)21-13(10)12/h1-7,20-21H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Université Curated by ChEMBL					Assay Description Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins				Bioorg Med Chem 18: 6865-73 (2010) Article DOI: 10.1016/j.bmc.2010.07.036 BindingDB Entry DOI: 10.7270/Q2PK0GBZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50326438 (9-trifluoromethyl-1,10-dihydropyrrolo[2,3-a]carbaz...) Show SMILES FC(F)(F)c1cccc2c1[nH]c1c2ccc2c(C=O)c[nH]c12 Show InChI InChI=1S/C16H9F3N2O/c17-16(18,19)12-3-1-2-10-11-5-4-9-8(7-22)6-20-14(9)15(11)21-13(10)12/h1-7,20-21H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Université Curated by ChEMBL					Assay Description Inhibition of human GST fused Pim1 expressed in Escherichia coli after 30 mins				Bioorg Med Chem 18: 6865-73 (2010) Article DOI: 10.1016/j.bmc.2010.07.036 BindingDB Entry DOI: 10.7270/Q2PK0GBZ
					More data for this Ligand-Target Pair