BDBM50326467 CHEMBL1243315::N-Benzyl-3,4'-dihydroxy-3',5'-dimethoxybiphenyl-4-carboxamide

SMILES: COc1cc(cc(OC)c1O)-c1ccc(C(=O)NCc2ccccc2)c(O)c1

InChI Key: InChIKey=XGHKGNLWTRRFHW-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50326467 (CHEMBL1243315 | N-Benzyl-3,4'-dihydroxy-3',5'-dime...) Show SMILES COc1cc(cc(OC)c1O)-c1ccc(C(=O)NCc2ccccc2)c(O)c1 Show InChI InChI=1S/C22H21NO5/c1-27-19-11-16(12-20(28-2)21(19)25)15-8-9-17(18(24)10-15)22(26)23-13-14-6-4-3-5-7-14/h3-12,24-25H,13H2,1-2H3,(H,23,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase after 30 mins by Lineweaver-Burk double reciprocal plot analysis				Bioorg Med Chem 18: 6708-14 (2010) Article DOI: 10.1016/j.bmc.2010.07.062 BindingDB Entry DOI: 10.7270/Q2JS9QN4
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50326467 (CHEMBL1243315 | N-Benzyl-3,4'-dihydroxy-3',5'-dime...) Show SMILES COc1cc(cc(OC)c1O)-c1ccc(C(=O)NCc2ccccc2)c(O)c1 Show InChI InChI=1S/C22H21NO5/c1-27-19-11-16(12-20(28-2)21(19)25)15-8-9-17(18(24)10-15)22(26)23-13-14-6-4-3-5-7-14/h3-12,24-25H,13H2,1-2H3,(H,23,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 30 mins				Bioorg Med Chem 18: 6708-14 (2010) Article DOI: 10.1016/j.bmc.2010.07.062 BindingDB Entry DOI: 10.7270/Q2JS9QN4
					More data for this Ligand-Target Pair