BDBM50326480 CHEMBL1243220::N1-(3,4-dihydroxyphenethyl)-N2-(3-nitrophenyl)oxalamide

SMILES: Oc1ccc(CCNC(=O)C(=O)Nc2cccc(c2)[N+]([O-])=O)cc1O

InChI Key: InChIKey=GJUYPXRPOBGIPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 4 (Homo sapiens (Human))	BDBM50326480 (CHEMBL1243220 | N1-(3,4-dihydroxyphenethyl)-N2-(3-...) Show SMILES Oc1ccc(CCNC(=O)C(=O)Nc2cccc(c2)[N+]([O-])=O)cc1O Show InChI InChI=1S/C16H15N3O6/c20-13-5-4-10(8-14(13)21)6-7-17-15(22)16(23)18-11-2-1-3-12(9-11)19(24)25/h1-5,8-9,20-21H,6-7H2,(H,17,22)(H,18,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vichem Chemie Research Ltd. Curated by ChEMBL					Assay Description Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay				J Med Chem 53: 6758-62 (2010) Article DOI: 10.1021/jm1004368 BindingDB Entry DOI: 10.7270/Q2F18ZZ5
					More data for this Ligand-Target Pair