new BindingDB logo
myBDB logout

BDBM50326495 2,3,8,9-tetrahydroxy-5-(2-hydroxy-5-nitrobenzyl)phenanthridin-6(5H)-one::CHEMBL1242941

SMILES: Oc1ccc(cc1Cn1c2cc(O)c(O)cc2c2cc(O)c(O)cc2c1=O)[N+]([O-])=O

InChI Key: InChIKey=ZVHQRCCECUCUQZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326495   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NADPH oxidase 4


(Homo sapiens (Human))
BDBM50326495
PNG
(2,3,8,9-tetrahydroxy-5-(2-hydroxy-5-nitrobenzyl)ph...)
Show SMILES Oc1ccc(cc1Cn1c2cc(O)c(O)cc2c2cc(O)c(O)cc2c1=O)[N+]([O-])=O
Show InChI InChI=1S/C20H14N2O8/c23-15-2-1-10(22(29)30)3-9(15)8-21-14-7-19(27)17(25)5-12(14)11-4-16(24)18(26)6-13(11)20(21)28/h1-7,23-27H,8H2
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Vichem Chemie Research Ltd.

Curated by ChEMBL


Assay Description
Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay


J Med Chem 53: 6758-62 (2010)


Article DOI: 10.1021/jm1004368
BindingDB Entry DOI: 10.7270/Q2F18ZZ5
More data for this
Ligand-Target Pair