BDBM50326557 (E)-5-((2-hydroxynaphthalen-1-yl)diazenyl)naphthalene-2-sulfonic acid::CHEMBL1253920::NSC45576, 2

SMILES: Oc1ccc2ccccc2c1N=Nc1cccc2cc(ccc12)S(O)(=O)=O

InChI Key: InChIKey=COUYJSSQPKTVIQ-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PhoP (Salmonella enterica)	BDBM50326557 ((E)-5-((2-hydroxynaphthalen-1-yl)diazenyl)naphthal...) Show SMILES Oc1ccc2ccccc2c1N=Nc1cccc2cc(ccc12)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C20H14N2O4S/c23-19-11-8-13-4-1-2-6-17(13)20(19)22-21-18-7-3-5-14-12-15(27(24,25)26)9-10-16(14)18/h1-12,23H,(H,24,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine					Assay Description Inhibition of a protein-protein activity by EMSA assay.				Chem Biol Drug Des 79: 1007-17 (2012) Article DOI: 10.1111/j.1747-0285.2012.01362.x BindingDB Entry DOI: 10.7270/Q2FJ2FC7
					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50326557 ((E)-5-((2-hydroxynaphthalen-1-yl)diazenyl)naphthal...) Show SMILES Oc1ccc2ccccc2c1N=Nc1cccc2cc(ccc12)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C20H14N2O4S/c23-19-11-8-13-4-1-2-6-17(13)20(19)22-21-18-7-3-5-14-12-15(27(24,25)26)9-10-16(14)18/h1-12,23H,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Displacement of 8-NBD-cAMP from EPAC2 (unknown origin) by fluorescence plate reader analysis				J Med Chem 57: 3651-65 (2014) Article DOI: 10.1021/jm401425e BindingDB Entry DOI: 10.7270/Q2WH2RJW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (PTPβ) (Homo sapiens (Human))	BDBM50326557 ((E)-5-((2-hydroxynaphthalen-1-yl)diazenyl)naphthal...) Show SMILES Oc1ccc2ccccc2c1N=Nc1cccc2cc(ccc12)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C20H14N2O4S/c23-19-11-8-13-4-1-2-6-17(13)20(19)22-21-18-7-3-5-14-12-15(27(24,25)26)9-10-16(14)18/h1-12,23H,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	5.0	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5				Bioorg Med Chem 18: 5449-56 (2010) Article DOI: 10.1016/j.bmc.2010.04.050 BindingDB Entry DOI: 10.7270/Q2Q52QMC
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase alpha (Homo sapiens (Human))	BDBM50326557 ((E)-5-((2-hydroxynaphthalen-1-yl)diazenyl)naphthal...) Show SMILES Oc1ccc2ccccc2c1N=Nc1cccc2cc(ccc12)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C20H14N2O4S/c23-19-11-8-13-4-1-2-6-17(13)20(19)22-21-18-7-3-5-14-12-15(27(24,25)26)9-10-16(14)18/h1-12,23H,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	5.0	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5				Bioorg Med Chem 18: 5449-56 (2010) Article DOI: 10.1016/j.bmc.2010.04.050 BindingDB Entry DOI: 10.7270/Q2Q52QMC
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase alpha (Homo sapiens (Human))	BDBM50326557 ((E)-5-((2-hydroxynaphthalen-1-yl)diazenyl)naphthal...) Show SMILES Oc1ccc2ccccc2c1N=Nc1cccc2cc(ccc12)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C20H14N2O4S/c23-19-11-8-13-4-1-2-6-17(13)20(19)22-21-18-7-3-5-14-12-15(27(24,25)26)9-10-16(14)18/h1-12,23H,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	7.0	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7				Bioorg Med Chem 18: 5449-56 (2010) Article DOI: 10.1016/j.bmc.2010.04.050 BindingDB Entry DOI: 10.7270/Q2Q52QMC
					More data for this Ligand-Target Pair