BDBM50326609 2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-pyrrolo[2,3-d]pyrimidine::CHEMBL1254199

SMILES: CN(c1cccc(Br)c1)c1nc(N)nc2[nH]c(Cc3ccccc3)cc12

InChI Key: InChIKey=SKKIJQLGOTXDRV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50326609 (2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-pyrro...) Show SMILES CN(c1cccc(Br)c1)c1nc(N)nc2[nH]c(Cc3ccccc3)cc12 Show InChI InChI=1S/C20H18BrN5/c1-26(16-9-5-8-14(21)11-16)19-17-12-15(10-13-6-3-2-4-7-13)23-18(17)24-20(22)25-19/h2-9,11-12H,10H2,1H3,(H3,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of EGFR expressed in human A431 cells				Bioorg Med Chem 18: 5261-73 (2010) Article DOI: 10.1016/j.bmc.2010.05.049 BindingDB Entry DOI: 10.7270/Q29Z95W6
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50326609 (2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-pyrro...) Show SMILES CN(c1cccc(Br)c1)c1nc(N)nc2[nH]c(Cc3ccccc3)cc12 Show InChI InChI=1S/C20H18BrN5/c1-26(16-9-5-8-14(21)11-16)19-17-12-15(10-13-6-3-2-4-7-13)23-18(17)24-20(22)25-19/h2-9,11-12H,10H2,1H3,(H3,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta expressed in human A431 cells				Bioorg Med Chem 18: 5261-73 (2010) Article DOI: 10.1016/j.bmc.2010.05.049 BindingDB Entry DOI: 10.7270/Q29Z95W6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50326609 (2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-pyrro...) Show SMILES CN(c1cccc(Br)c1)c1nc(N)nc2[nH]c(Cc3ccccc3)cc12 Show InChI InChI=1S/C20H18BrN5/c1-26(16-9-5-8-14(21)11-16)19-17-12-15(10-13-6-3-2-4-7-13)23-18(17)24-20(22)25-19/h2-9,11-12H,10H2,1H3,(H3,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 expressed in human A431 cells				Bioorg Med Chem 18: 5261-73 (2010) Article DOI: 10.1016/j.bmc.2010.05.049 BindingDB Entry DOI: 10.7270/Q29Z95W6
					More data for this Ligand-Target Pair